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Pathways of ammonia detoxification to GLN in muscles linked to enhanced usage with the BCAA and α-KG (cataplerosis) and advised results of BCAA and phenylbutyrate in subjects with liver cirrhosis or UCD. Constructive influence of BCAA on ammonia detoxification to GLN might be blunted by GLN degradation to ammonia in enterocytes and kidneys. Phenyl